MASS SPECTROMETRY:INSTRUMENTATION INTERPRETATION AND APPLICATIONS

With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.Review’It was my great pleasure to read this clearly written and well organized mass spectrometry (MS) book. In view, it can serve as an excellent textbook for both undergraduate and graduate students who major in analytical, biological, forensic, or environmental chemistry, as well as a valuable resource to those researchers who are interested in the MS-based chemical analysis.’ (J Am Soc Mass Spectrom, 2011) ‘The book is particularly designed for graduate students, with the assumption being made that most of them will not become mass spectrometry specialists. Instead, it focuses on how they can use the technique to support and advance research across a broad range of disciplines.’ (Chemistry Journals, 11 April 2011)From the Inside FlapHelps students fully leverage mass spectrometry in whichever field of research they choose Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.This text is divided into three parts that guide students from basic principles to applications:Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.From the Back CoverHelps students fully leverage mass spectrometry in whichever field of research they choose Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorgani